Miscellaneous RNA processing factors

Gene Name Onco-Tools Products Description Gene Type NCBI Gene ID Ensembl Gene
AGO2 argonaute 2, RISC catalytic component M-AGO2-TB1

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain.

Protein-Coding 27161 ENSG00000123908
BOP1 block of proliferation 1 M-BOP1-TB1, M-BOP1-TB2 Protein-Coding 23246 ENSG00000261236
CLK1 CDC like kinase 1 M-CLK1-TB1, M-CLK1-TB2, M-CLK1-TB3, M-CLK1-TB4

This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases.

Protein-Coding 1195 ENSG00000013441
CLK4 CDC like kinase 4 M-CLK4-TB1, M-CLK4-TB2

The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family.

Protein-Coding 57396 ENSG00000113240
CSTF2 cleavage stimulation factor subunit 2 M-CSTF2-TB1, M-CSTF2-TB2

This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain.

Protein-Coding 1478 ENSG00000101811
DDX1 DEAD-box helicase 1 M-DDX1-TB1, M-DDX1-TB2

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases.

Protein-Coding 1653 ENSG00000079785
DDX43 DEAD-box helicase 43 M-DDX43-TB1, M-DDX43-TB2

The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression. [provided by RefSeq, Jul 2008]

Protein-Coding 55510 ENSG00000080007
DDX5 DEAD-box helicase 5 M-DDX5-TB1, M-DDX5-TB2

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases.

Protein-Coding 1655 ENSG00000108654
DDX6 DEAD-box helicase 6 M-DDX6-TB1, M-DDX6-TB2

This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation.

Protein-Coding 1656 ENSG00000110367
DHX9 DExH-box helicase 9 M-DHX9-TB1, M-DHX9-TB2

This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes.

Protein-Coding 1660 ENSG00000135829
DICER1 dicer 1, ribonuclease III

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus.

Protein-Coding 23405 ENSG00000100697
EEF1A2 eukaryotic translation elongation factor 1 alpha 2

This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome.

Protein-Coding 1917 ENSG00000101210
EEF2 eukaryotic translation elongation factor 2

This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis.

Protein-Coding 1938 ENSG00000167658
EEF2K eukaryotic elongation factor 2 kinase

This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division.

Protein-Coding 29904 ENSG00000103319
EIF3H eukaryotic translation initiation factor 3 subunit H Protein-Coding 8667 ENSG00000147677
EIF4A1 eukaryotic translation initiation factor 4A1 Protein-Coding 1973 ENSG00000161960
EIF4A3 eukaryotic translation initiation factor 4A3

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases.

Protein-Coding 9775 ENSG00000141543
EIF4E eukaryotic translation initiation factor 4E

The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs

Protein-Coding 1977 ENSG00000151247
EIF4G1 eukaryotic translation initiation factor 4 gamma 1

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F.

Protein-Coding 1981 ENSG00000114867
EIF5A eukaryotic translation initiation factor 5A Protein-Coding 1984 ENSG00000132507
EIF5A2 eukaryotic translation initiation factor 5A2 Protein-Coding 56648 ENSG00000163577
EIF6 eukaryotic translation initiation factor 6

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton.

Protein-Coding 3692 ENSG00000242372
ELAVL1 ELAV like RNA binding protein 1

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3

Protein-Coding 1994 ENSG00000066044
ELAVL4 ELAV like RNA binding protein 4 Protein-Coding 1996 ENSG00000162374
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1

This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and i

Protein-Coding 3178 ENSG00000135486
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).

Protein-Coding 3181 ENSG00000122566
HNRNPF heterogeneous nuclear ribonucleoprotein F

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).

Protein-Coding 3185 ENSG00000169813
HNRNPK heterogeneous nuclear ribonucleoprotein K

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).

Protein-Coding 3190 ENSG00000165119
HNRNPL heterogeneous nuclear ribonucleoprotein L

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes.

Protein-Coding 3191 ENSG00000104824
KHDRBS1 KH RNA binding domain containing, signal transduction associated 1

This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family.

Protein-Coding 10657 ENSG00000121774
KHDRBS3 KH RNA binding domain containing, signal transduction associated 3 Protein-Coding 10656 ENSG00000131773
LSM1 LSM1 homolog, mRNA degradation associated

This gene encodes a member of the LSm family of RNA-binding proteins.

Protein-Coding 27257 ENSG00000175324
MALAT-1 metastasis associated lung adenocarcinoma transcript 1

This gene produces a precursor transcript from which a long non-coding RNA is derived by RNase P cleavage of a tRNA-like small ncRNA (known as mascRNA) from its 3' end.

Non-Coding 378938
NOVA1 NOVA alternative splicing regulator 1

This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies.

Protein-Coding 4857 ENSG00000139910
NPM1 nucleophosmin

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway.

Protein-Coding 4869 ENSG00000181163
PCBP2 poly(rC) binding protein 2

The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins.

Protein-Coding 5094 ENSG00000197111
PTBP1 polypyrimidine tract binding protein 1

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).

Protein-Coding 5725 ENSG00000011304
PTBP2 polypyrimidine tract binding protein 2

The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins.

Protein-Coding 58155 ENSG00000117569
RBM17 RNA binding motif protein 17

This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing.

Protein-Coding 84991 ENSG00000134453
RBM3 RNA binding motif (RNP1, RRM) protein 3

This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain.

Protein-Coding 5935 ENSG00000102317
RBM5 RNA binding motif protein 5

This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex.

Protein-Coding 10181 ENSG00000003756
SF1 splicing factor 1

This gene encodes a nuclear pre-mRNA splicing factor.

Protein-Coding 7536 ENSG00000168066
SF3A1 splicing factor 3a subunit 1

This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP).

Protein-Coding 10291 ENSG00000099995
SF3B6 splicing factor 3b subunit 6

This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex.

Protein-Coding 51639 ENSG00000115128
SRPK1 SRSF protein kinase 1

This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm.

Protein-Coding 6732 ENSG00000096063
SRPK2 SRSF protein kinase 2 Protein-Coding 6733 ENSG00000135250
SRRM1 serine and arginine repetitive matrix 1 Protein-Coding 10250 ENSG00000133226
SRSF1 serine and arginine rich splicing factor 1

This gene encodes a member of the arginine/serine-rich splicing factor protein family.

Protein-Coding 6426 ENSG00000136450
SRSF10 serine and arginine rich splicing factor 10

This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing.

Protein-Coding 10772 ENSG00000188529
SRSF2 serine and arginine rich splicing factor 2

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome.

Protein-Coding 6427 ENSG00000161547
SRSF3 serine and arginine rich splicing factor 3

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome.

Protein-Coding 6428 ENSG00000112081
SRSF5 serine and arginine rich splicing factor 5

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome.

Protein-Coding 6430 ENSG00000100650
SRSF6 serine and arginine rich splicing factor 6

The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing.

Protein-Coding 6431 ENSG00000124193
SSB Sjogren syndrome antigen B

The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digest

Protein-Coding 6741 ENSG00000138385
TARDBP TAR DNA binding protein

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle.

Protein-Coding 23435 ENSG00000120948
U2AF1 U2 small nuclear RNA auxiliary factor 1

This gene belongs to the splicing factor SR family of genes.

Protein-Coding 7307 ENSG00000160201
U2AF2 U2 small nuclear RNA auxiliary factor 2

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site.

Protein-Coding 11338 ENSG00000063244
UBTF upstream binding transcription factor, RNA polymerase I

This gene encodes a member of the HMG-box DNA-binding protein family.

Protein-Coding 7343 ENSG00000108312
WT1 Wilms tumor 1

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus.

Protein-Coding 7490 ENSG00000184937
WTAP Wilms tumor 1 associated protein

The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes.

Protein-Coding 9589 ENSG00000146457
YBX1 Y-box binding protein 1

This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties.

Protein-Coding 4904 ENSG00000065978