Metastasis

Gene Name Onco-Tools Products Description Gene Type NCBI Gene ID Ensembl Gene
CCL7 C-C motif chemokine ligand 7 M-CCL7-TB1, M-CCL7-TB2

This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis.

Protein-Coding 6354 ENSG00000108688
CD82 CD82 molecule M-CD82-TB1, M-CD82-TB2

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily.

Protein-Coding 3732 ENSG00000085117
CDH11 cadherin 11 M-CDH11-TB1, M-CDH11-TB2

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion.

Protein-Coding 1009 ENSG00000140937
CDH6 cadherin 6 M-CDH6-TB1, M-CDH6-TB2

This gene encodes a member of the cadherin superfamily.

Protein-Coding 1004 ENSG00000113361
COL4A2 collagen type IV alpha 2 chain M-COL4A2-TB1, M-COL4A2-TB2

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes.

Protein-Coding 1284 ENSG00000134871
CST7 cystatin F M-CST7-TB1, M-CST7-TB2

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences.

Protein-Coding 8530 ENSG00000077984
CTSK cathepsin K M-CTSK-TB1, M-CTSK-TB2

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption.

Protein-Coding 1513 ENSG00000143387
CTSL cathepsin L M-CTSL-TB1, M-CTSL-TB2, M-CTSL-TB3

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism.

Protein-Coding 1514 ENSG00000135047
CXCL12 C-X-C motif chemokine ligand 12 M-CXCL12-TB1, M-CXCL12-TB2

This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family.

Protein-Coding 6387 ENSG00000107562
CXCR2 C-X-C motif chemokine receptor 2 M-CXCR2-TB1, M-CXCR2-TB2

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8).

Protein-Coding 3579 ENSG00000180871
CXCR4 C-X-C motif chemokine receptor 4

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface.

Protein-Coding 7852 ENSG00000121966
DANCR differentiation antagonizing non-protein coding RNA

This gene produces a long non-coding RNA that functions as a negative regulator of cell differentiation.

Non-Coding 57291 ENSG00000226950
EPHB2 EPH receptor B2 M-EPHB2-TB1, M-EPHB2-TB2

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins.

Protein-Coding 2048 ENSG00000133216
FAT1 FAT atypical cadherin 1 M-FAT1-TB1, M-FAT1-TB2

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development.

Protein-Coding 2195 ENSG00000083857
FGFR4 fibroblast growth factor receptor 4 M-FGFR4-TB1, M-FGFR4-TB2

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution.

Protein-Coding 2264 ENSG00000160867
FN1 fibronectin 1 M-FN1-TB1, M-FN1-TB2

This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix.

Protein-Coding 2335 ENSG00000115414
FXYD5 FXYD domain containing ion transport regulator 5

This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly con

Protein-Coding 53827 ENSG00000089327
HPSE heparanase M-HPSE-TB1

Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix.

Protein-Coding 10855 ENSG00000173083
IL18 interleukin 18 M-IL18-TB1, M-IL18-TB2

The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells.

Protein-Coding 3606 ENSG00000150782
IL1B interleukin 1 beta M-IL1B-TB1, M-IL1B-TB2, M-IL1B-TB3, M-IL1B-TB4

The protein encoded by this gene is a member of the interleukin 1 cytokine family.

Protein-Coding 3553 ENSG00000125538
ITGA7 integrin subunit alpha 7 M-ITGA7-TB1, M-ITGA7-TB2, M-ITGA7-TB3, M-ITGA7-TB4

The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.

Protein-Coding 3679 ENSG00000135424
ITGB3 integrin subunit beta 3

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain.

Protein-Coding 3690 ENSG00000259207
KISS1R KISS1 receptor

The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1.

Protein-Coding 84634 ENSG00000116014
MCAM melanoma cell adhesion molecule Protein-Coding 4162 ENSG00000076706
MET MET proto-oncogene, receptor tyrosine kinase

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET.

Protein-Coding 4233 ENSG00000105976
METAP2 methionyl aminopeptidase 2

The protein encoded by this gene is a member of the methionyl aminopeptidase family.

Protein-Coding 10988 ENSG00000111142
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase

The protein encoded by this gene belongs to the glycosyltransferase family.

Protein-Coding 4249 ENSG00000152127
MIR10B microRNA 10b

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 406903 ENSG00000207744
MIR122 microRNA 122

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 406906 ENSG00000284440
MIR182 microRNA 182

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 406958 ENSG00000207990
MIR21 microRNA 21 M-MIR21-TB1, M-MIR21-TB2

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 406991 ENSG00000284190
MIR22 microRNA 22

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 407004 ENSG00000283824
MIR9-1 microRNA 9-1

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 407046 ENSG00000207933
MMP10 matrix metallopeptidase 10

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs).

Protein-Coding 4319 ENSG00000166670
MMP11 matrix metallopeptidase 11

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissu

Protein-Coding 4320 ENSG00000099953,ENSG00000275365
MMP13 matrix metallopeptidase 13

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs).

Protein-Coding 4322 ENSG00000137745
MMP2 matrix metallopeptidase 2

This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal

Protein-Coding 4313 ENSG00000087245
MMP3 matrix metallopeptidase 3

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissu

Protein-Coding 4314 ENSG00000149968
MMP7 matrix metallopeptidase 7

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs).

Protein-Coding 4316 ENSG00000137673
MMP9 matrix metallopeptidase 9

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissu

Protein-Coding 4318 ENSG00000100985
MTSS1 MTSS1, I-BAR domain containing Protein-Coding 9788 ENSG00000170873
NME1 NME/NM23 nucleoside diphosphate kinase 1

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells.

Protein-Coding 4830 ENSG00000239672
NME4 NME/NM23 nucleoside diphosphate kinase 4

The nucleoside diphosphate (NDP) kinases (EC 2.7.4.6) are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside

Protein-Coding 4833 ENSG00000103202
NR4A3 nuclear receptor subfamily 4 group A member 3

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator.

Protein-Coding 8013 ENSG00000119508
PLAUR plasminogen activator, urokinase receptor

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes relate

Protein-Coding 5329 ENSG00000011422
PNN pinin, desmosome associated protein Protein-Coding 5411 ENSG00000100941
SSTR2 somatostatin receptor 2

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins.

Protein-Coding 6752 ENSG00000180616
SYK spleen associated tyrosine kinase

This gene encodes a member of the family of non-receptor type Tyr protein kinases.

Protein-Coding 6850 ENSG00000165025
TIMP2 TIMP metallopeptidase inhibitor 2

This gene is a member of the TIMP gene family.

Protein-Coding 7077 ENSG00000035862
TIMP3 TIMP metallopeptidase inhibitor 3

This gene belongs to the TIMP gene family.

Protein-Coding 7078 ENSG00000100234
TIMP4 TIMP metallopeptidase inhibitor 4

This gene belongs to the TIMP gene family.

Protein-Coding 7079 ENSG00000157150
TNFSF10 tumor necrosis factor superfamily member 10 M-TNFSF10-TB1, M-TNFSF10-TB2

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.

Protein-Coding 8743 ENSG00000121858
TSHR thyroid stimulating hormone receptor

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism.

Protein-Coding 7253 ENSG00000165409