Inflammation

Gene Name Onco-Tools Products Description Gene Type NCBI Gene ID Ensembl Gene
CCL2 C-C motif chemokine ligand 2 M-CCL2-TB1, M-CCL2-TB2

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes.

Protein-Coding 6347 ENSG00000108691
CCL20 C-C motif chemokine ligand 20 M-CCL20-TB1, M-CCL20-TB2

This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes.

Protein-Coding 6364 ENSG00000115009
CCL3L1 C-C motif chemokine ligand 3 like 1 M-CCL3L1-TB1, M-CCL3L1-TB2

This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17.

Protein-Coding 6349
CCL5 C-C motif chemokine ligand 5 M-CCL5-TB1, M-CCL5-TB2

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes.

Protein-Coding 6352 ENSG00000271503
CFLAR CASP8 and FADD like apoptosis regulator M-CFLAR-TB1, M-CFLAR-TB2, M-CFLAR-TB3, M-CFLAR-TB4

The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8.

Protein-Coding 8837 ENSG00000003402
CXCL1 C-X-C motif chemokine ligand 1

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2.

Protein-Coding 2919 ENSG00000163739
IFNG interferon gamma M-IFNG-TB1, M-IFNG-TB2

This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems.

Protein-Coding 3458 ENSG00000111537
IL10 interleukin 10 M-IL10-TB1

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation.

Protein-Coding 3586 ENSG00000136634
IL12A interleukin 12A M-IL12A-TB1, M-IL12A-TB2

This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities.

Protein-Coding 3592 ENSG00000168811
IL12B interleukin 12B M-IL12B-TB1, M-IL12B-TB2

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities.

Protein-Coding 3593 ENSG00000113302
IL13 interleukin 13

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation.

Protein-Coding 3596 ENSG00000169194
IL17A interleukin 17A M-IL17A-TB1, M-IL17A-TB2

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases.

Protein-Coding 3605 ENSG00000112115
IL1A interleukin 1 alpha M-IL1A-TB1, M-IL1A-TB2

The protein encoded by this gene is a member of the interleukin 1 cytokine family.

Protein-Coding 3552 ENSG00000115008
IL1B interleukin 1 beta M-IL1B-TB1, M-IL1B-TB2, M-IL1B-TB3, M-IL1B-TB4

The protein encoded by this gene is a member of the interleukin 1 cytokine family.

Protein-Coding 3553 ENSG00000125538
IL1R1 interleukin 1 receptor type 1

This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family.

Protein-Coding 3554 ENSG00000115594
IL2 interleukin 2 M-IL2-TB1

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes.

Protein-Coding 3558 ENSG00000109471
IL23A interleukin 23 subunit alpha M-IL23A-TB1, M-IL23A-TB2

This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B).

Protein-Coding 51561 ENSG00000110944
IL4 interleukin 4 M-IL4-TB1, M-IL4-TB2

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor.

Protein-Coding 3565 ENSG00000113520
IL6 interleukin 6 M-IL6-TB1, M-IL6-TB2, M-IL6-TB3, M-IL6-TB4

This gene encodes a cytokine that functions in inflammation and the maturation of B cells.

Protein-Coding 3569 ENSG00000136244
IL8 C-X-C motif chemokine ligand 8 M-IL8-TB1, M-IL8-TB2

The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response.

Protein-Coding 3576 ENSG00000169429
MIR132 microRNA 132 M-MIR132-TB1, M-MIR132-TB2

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 406921 ENSG00000267200
MIR146A microRNA 146a M-MIR146A-TB1

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 406938 ENSG00000283733
MIR21 microRNA 21 M-MIR21-TB1, M-MIR21-TB2

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 406991 ENSG00000284190
MIR214 microRNA 214 M-MIR214-TB1

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 406996 ENSG00000283844
MIR223 microRNA 223 M-MIR223-TB1

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 407008 ENSG00000284567
MIR224 microRNA 224 M-MIR224-TB1

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 407009 ENSG00000284363
MIR98 microRNA 98 M-MIR98-TB1

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and transl

Non-Coding 407054 ENSG00000271886
NFKB1 nuclear factor kappa B subunit 1 M-NFKB1-TB1, M-NFKB1-TB2

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein.

Protein-Coding 4790 ENSG00000109320
NFKB2 nuclear factor kappa B subunit 2 M-NFKB2-TB1, M-NFKB2-TB2

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB).

Protein-Coding 4791 ENSG00000077150
NOS2 nitric oxide synthase 2 M-NOS2-TB1, M-NOS2-TB2

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities.

Protein-Coding 4843 ENSG00000007171
PTGS2 prostaglandin-endoperoxide synthase 2 M-PTGS2-TB1

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase.

Protein-Coding 5743 ENSG00000073756
TLR4 toll like receptor 4 M-TLR4-TB1, M-TLR4-TB2, M-TLR4-TB3, M-TLR4-TB4, M-TLR4-TB5, M-TLR4-TB6

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity.

Protein-Coding 7099 ENSG00000136869
TNF tumor necrosis factor M-TNF-TB1, M-TNF-TB2, M-TNF-TB3

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages.

Protein-Coding 7124
TNFRSF1A TNF receptor superfamily member 1A M-TNFRSF1A-TB1, M-TNFRSF1A-TB2

This gene encodes a member of the TNF receptor superfamily of proteins.

Protein-Coding 7132 ENSG00000067182
TRAF2 TNF receptor associated factor 2 M-TRAF2-TB1

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family.

Protein-Coding 7186 ENSG00000127191
TRAF6 TNF receptor associated factor 6 M-TRAF6-TB1, M-TRAF6-TB2, M-TRAF6-TB3

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family.

Protein-Coding 7189 ENSG00000175104