ATR

Full Name: 
ATR serine/threonine kinase
Aliases: 
FRP1; MEC1; SCKL; FCTCS; SCKL1
Gene Type: 
Protein-Coding

The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008]

M-ATR-TB1

Title:
M-ATR-TB1-100n
SKU:
M1402-1A
Species: 
Hs
Product Type: 
Translation Blocker
Transcript Type: 
Protein-Coding
Target Region: 

gtagctttgg agacgccggg aacccgcgtt ggcgtggttg actagtgcct cgcagcctca gc(atg)gggga acatggcctg gagctgg

Price: 
$250.00

M-ATR-TB2

Title:
M-ATR-TB2-100n
SKU:
M1402-2A
Species: 
Hs
Product Type: 
Translation Blocker
Transcript Type: 
Protein-Coding
Target Region: 

gtagctttgg agacgccggg aacccgcgtt ggcgtggttg actagtgcct cgcagcctca gc(atg)gggga acatggcctg gagctgg

Price: 
$250.00