ACLY

Categories: 
Full Name: 
ATP citrate lyase
Aliases: 
ACL; ATPCL; CLATP
Gene Type: 
Protein-Coding

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]

M-ACLY-TB1

Title:
M-ACLY-TB1-100n
SKU:
M2001-1A
Species: 
Hs
Product Type: 
Translation Blocker
Transcript Type: 
Protein-Coding
Target Region: 

tggggtgctc cggattttgc ggggttcgtc gggcctgtgg aagaagcgcc gcgcacggac ttcggcagag gtagagcagg tctctctgca gcc(atg)tcgg ccaaggcaat ttcagagc

Price: 
$250.00

M-ACLY-TB2

Title:
M-ACLY-TB2-100n
SKU:
M2001-2A
Species: 
Hs
Product Type: 
Translation Blocker
Transcript Type: 
Protein-Coding
Target Region: 

tggggtgctc cggattttgc ggggttcgtc gggcctgtgg aagaagcgcc gcgcacggac ttcggcagag gtagagcagg tctctctgca gcc(atg)tcgg ccaaggcaat ttcagagc

Price: 
$250.00

M-ACLY-TB3

Title:
M-ACLY-TB3-100n
SKU:
M2001-3A
Species: 
Hs
Product Type: 
Translation Blocker
Transcript Type: 
Protein-Coding
Target Region: 

gcgagccg(atg)ggggcgggg aaaagtccgg ctg

Price: 
$250.00