Genes Listed Alphabetically

A (18) | B (30) | C (85) | D (12) | E (24) | F (18) | G (5) | H (26) | I (29) | J (2) | K (21) | L (3) | M (69) | N (16) | P (29) | R (26) | S (36) | T (30) | U (4) | V (5) | W (5) | X (2) | Y (1)
Gene Name Onco-Tools Products Description Categories Gene Type NCBI Gene ID Ensembl Gene
AXIN1 axin 1 M-AXIN1-TB1, M-AXIN1-TB2

This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain.

Cell Signaling Protein-Coding 8312 ENSG00000103126
AURKA aurora kinase A

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation.

Cell Cycle & DNA Repair Protein-Coding 6790 ENSG00000087586
ATR ATR serine/threonine kinase M-ATR-TB1, M-ATR-TB2

The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia.

Cell Cycle & DNA Repair Protein-Coding 545 ENSG00000175054
ATM ATM serine/threonine kinase M-ATM-TB1

The protein encoded by this gene belongs to the PI3/PI4-kinase family.

Cell Cycle & DNA Repair Protein-Coding 472 ENSG00000149311
AR androgen receptor M-AR-TB1, M-AR-TB2

The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain.

Cell Signaling Protein-Coding 367 ENSG00000169083
APC APC, WNT signaling pathway regulator

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway.

Cell Signaling Protein-Coding 324 ENSG00000134982
APAF1 apoptotic peptidase activating factor 1 M-APAF1-TB1, M-APAF1-TB2

This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC).

Apoptosis Protein-Coding 317 ENSG00000120868
ANGPTL4 angiopoietin like 4 M-ANGPTL4-TB1, M-ANGPTL4-TB2

This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain.

Angiogenesis Protein-Coding 51129 ENSG00000167772
ANGPTL3 angiopoietin like 3 M-ANGPTL3-TB1, M-ANGPTL3-TB2

This gene encodes a member of a family of secreted proteins that function in angiogenesis.

Angiogenesis Protein-Coding 27329 ENSG00000132855
ANGPT2 angiopoietin 2 M-ANGPT2-TB1, M-ANGPT2-TB2

The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK).

Angiogenesis Protein-Coding 285 ENSG00000091879
ANGPT1 angiopoietin 1

This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis.

Angiogenesis Protein-Coding 284 ENSG00000154188
AKT2 AKT serine/threonine kinase 2

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains.

Cell Signaling Protein-Coding 208 ENSG00000105221
AKT1 AKT serine/threonine kinase 1 M-AKT1-TB1, M-AKT1-TB2

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts.

Cell Signaling Protein-Coding 207 ENSG00000142208
AIFM1 apoptosis inducing factor mitochondria associated 1 M-AIFM1-TB1, M-AIFM1-TB2

This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells.

Apoptosis Protein-Coding 9131 ENSG00000156709
AGO2 argonaute 2, RISC catalytic component M-AGO2-TB1

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain.

Miscellaneous RNA processing factors Protein-Coding 27161 ENSG00000123908
ADGRB1 adhesion G protein-coupled receptor B1 M-ADGRB1-TB1, M-ADGRB1-TB2

Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions.

Angiogenesis Protein-Coding 575 ENSG00000181790
ACLY ATP citrate lyase M-ACLY-TB1, M-ACLY-TB2, M-ACLY-TB3

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues.

Abnormal Metabolism Protein-Coding 47 ENSG00000131473
ACACA acetyl-CoA carboxylase alpha

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system.

Abnormal Metabolism Protein-Coding 31 ENSG00000278540