Genes Listed Alphabetically
|Gene||Name||Onco-Tools Products||Description||Categories||Gene Type||NCBI Gene ID||Ensembl Gene|
|AXIN1||axin 1||M-AXIN1-TB1, M-AXIN1-TB2||
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain.
|AURKA||aurora kinase A||
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation.
|Cell Cycle & DNA Repair||Protein-Coding||6790||ENSG00000087586|
|ATR||ATR serine/threonine kinase||M-ATR-TB1, M-ATR-TB2||
The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia.
|Cell Cycle & DNA Repair||Protein-Coding||545||ENSG00000175054|
|ATM||ATM serine/threonine kinase||M-ATM-TB1||
The protein encoded by this gene belongs to the PI3/PI4-kinase family.
|Cell Cycle & DNA Repair||Protein-Coding||472||ENSG00000149311|
|AR||androgen receptor||M-AR-TB1, M-AR-TB2||
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain.
|APC||APC, WNT signaling pathway regulator||
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway.
|APAF1||apoptotic peptidase activating factor 1||M-APAF1-TB1, M-APAF1-TB2||
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC).
|ANGPTL4||angiopoietin like 4||M-ANGPTL4-TB1, M-ANGPTL4-TB2||
This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain.
|ANGPTL3||angiopoietin like 3||M-ANGPTL3-TB1, M-ANGPTL3-TB2||
This gene encodes a member of a family of secreted proteins that function in angiogenesis.
|ANGPT2||angiopoietin 2||M-ANGPT2-TB1, M-ANGPT2-TB2||
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK).
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis.
|AKT2||AKT serine/threonine kinase 2||
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains.
|AKT1||AKT serine/threonine kinase 1||M-AKT1-TB1, M-AKT1-TB2||
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts.
|AIFM1||apoptosis inducing factor mitochondria associated 1||M-AIFM1-TB1, M-AIFM1-TB2||
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells.
|AGO2||argonaute 2, RISC catalytic component||M-AGO2-TB1||
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain.
|Miscellaneous RNA processing factors||Protein-Coding||27161||ENSG00000123908|
|ADGRB1||adhesion G protein-coupled receptor B1||M-ADGRB1-TB1, M-ADGRB1-TB2||
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions.
|ACLY||ATP citrate lyase||M-ACLY-TB1, M-ACLY-TB2, M-ACLY-TB3||
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues.
|ACACA||acetyl-CoA carboxylase alpha||
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system.