Genes Listed Alphabetically
Gene | Name | Onco-Tools Products | Description | Categories | Gene Type | NCBI Gene ID | Ensembl Gene |
---|---|---|---|---|---|---|---|
ACACA | acetyl-CoA carboxylase alpha |
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. |
Abnormal Metabolism | Protein-Coding | 31 | ENSG00000278540 | |
ACLY | ATP citrate lyase | M-ACLY-TB1, M-ACLY-TB2, M-ACLY-TB3 |
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. |
Abnormal Metabolism | Protein-Coding | 47 | ENSG00000131473 |
ADGRB1 | adhesion G protein-coupled receptor B1 | M-ADGRB1-TB1, M-ADGRB1-TB2 |
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. |
Angiogenesis | Protein-Coding | 575 | ENSG00000181790 |
AGO2 | argonaute 2, RISC catalytic component | M-AGO2-TB1 |
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. |
Miscellaneous RNA processing factors | Protein-Coding | 27161 | ENSG00000123908 |
AIFM1 | apoptosis inducing factor mitochondria associated 1 | M-AIFM1-TB1, M-AIFM1-TB2 |
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. |
Apoptosis | Protein-Coding | 9131 | ENSG00000156709 |
AKT1 | AKT serine/threonine kinase 1 | M-AKT1-TB1, M-AKT1-TB2 |
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. |
Cell Signaling | Protein-Coding | 207 | ENSG00000142208 |
AKT2 | AKT serine/threonine kinase 2 |
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. |
Cell Signaling | Protein-Coding | 208 | ENSG00000105221 | |
ANGPT1 | angiopoietin 1 |
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. |
Angiogenesis | Protein-Coding | 284 | ENSG00000154188 | |
ANGPT2 | angiopoietin 2 | M-ANGPT2-TB1, M-ANGPT2-TB2 |
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). |
Angiogenesis | Protein-Coding | 285 | ENSG00000091879 |
ANGPTL3 | angiopoietin like 3 | M-ANGPTL3-TB1, M-ANGPTL3-TB2 |
This gene encodes a member of a family of secreted proteins that function in angiogenesis. |
Angiogenesis | Protein-Coding | 27329 | ENSG00000132855 |
ANGPTL4 | angiopoietin like 4 | M-ANGPTL4-TB1, M-ANGPTL4-TB2 |
This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. |
Angiogenesis | Protein-Coding | 51129 | ENSG00000167772 |
APAF1 | apoptotic peptidase activating factor 1 | M-APAF1-TB1, M-APAF1-TB2 |
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). |
Apoptosis | Protein-Coding | 317 | ENSG00000120868 |
APC | APC, WNT signaling pathway regulator |
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. |
Cell Signaling | Protein-Coding | 324 | ENSG00000134982 | |
AR | androgen receptor | M-AR-TB1, M-AR-TB2 |
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. |
Cell Signaling | Protein-Coding | 367 | ENSG00000169083 |
ATM | ATM serine/threonine kinase | M-ATM-TB1 |
The protein encoded by this gene belongs to the PI3/PI4-kinase family. |
Cell Cycle & DNA Repair | Protein-Coding | 472 | ENSG00000149311 |
ATR | ATR serine/threonine kinase | M-ATR-TB1, M-ATR-TB2 |
The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. |
Cell Cycle & DNA Repair | Protein-Coding | 545 | ENSG00000175054 |
AURKA | aurora kinase A |
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. |
Cell Cycle & DNA Repair | Protein-Coding | 6790 | ENSG00000087586 | |
AXIN1 | axin 1 | M-AXIN1-TB1, M-AXIN1-TB2 |
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. |
Cell Signaling | Protein-Coding | 8312 | ENSG00000103126 |